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    Supported by Prof. Dr. Günther Enderlein who was 11 years elder, Wilhelm von Brehmer was the leader of the pathologic anatomic micro-chemical laboratory of the biologic ”Reichsanstalt” a state registered research institute in Berlin-Dahlem. He dedicated his life to the excessive research of endobionts  ( see live blood ), especially in connection with cancer, and gave the endobiont the name ”Siphonospora polymorpha”. He described every single state of the development in minute detail of ”Siphonospora polymorpha” and discovered its’ connection with cancer.

    The cyclic development of ”Siphonospora polymorpha” begins with the formation of spores and spore cases inside the erythrocyte. The spores growth rate depends on the bloods’ pH-value and splits into either two or four new spores. The higher the pH-value of the blood, the more the spores combine into double and tetra spores while the spore case is growing. Then the spore cases burst and release the spores. With continuous changes of the pH-value of the blood, the germination into rod-shaped spores takes place, which then disintegrate and release nucleoli and final germs, which can grow into rods again. If the process is malignant, the rods, as typical parasites, have the power to destroy the erythrocytes progressively by affecting the nuclei and pathologically splitting them. In addition, due to the progressive development of ”Siphonospora polymorpha” the erythrocytes become clumpy. This leads to a reduced oxygen supply in the body and results in a lack of energy because as we know, oxygen is necessary for the generation of energy.

    Wilhelm v. Brehmer developed a modified Gram-Weigert stain of the blood, which uncovers very clearly the states of development of endobionts or ”Siphonospora polymorpha” in erythrocytes and in plasma. This colouring is the basis of the blood microbes test.